Where are we?
What do we do?
We develop and use non-contact, non-invasive optical imaging tools to study structural and functional disorders in biological tissue with high spatiotemporal resolution.
Using phase- and polarization-sensitive interferometric techniques, we image tissue microstructure in real-time with a few micron spatial resolution and function with sub-nanometer scale optical path length resolution.
Functional recovery may be possible only when the tissue structure is intact; therefore, detecting structural changes (function) during physiological activity prior to any structural loss or permanent damage is the main thrust of our work.
Non-invasive or minimally invasive applications in medicine are possible, since the techniques use back-scattered light.
Our contributions to the field include (i) Brain imaging and mapping with serial optical coherence scanner, (ii) Depth-resolved optical imaging of neural action potentials, (iii) Integrating polarization-maintaining fiber technology into optical coherence tomography, and (iv) Differential phase sensors for ultrasensitive detection. For further information, please see the Research and Publications sections.
Structural & Functional Neuroimaging
Starting from summer 2020, the assistantship will provide support for Tianqi for 12 months. Congratulations to her!
Chao Liu has successfully defended his Ph.D. dissertation. Congratulations Dr. Liu!
Peter Howell completed his master's thesis succesfully. Congratulations to Peter!